Tristan McKinnon, Deterministic Systems Lab and Axle Informatics
Non-Human Identity is the fastest-growing attack surface in cloud data environments — and the least discussed. While zero-trust implementations focus on user authentication and network segmentation, the persistent service accounts powering automated pipelines remain long-lived, over-privileged, and largely unexamined. In federal healthcare environments processing genomic and clinical data under FedRAMP High constraints, a single compromised ingestion role means bucket-wide access for up to 90 days. That is not least privilege. That is a liability.
This talk is a production case study, not a proposal. We deployed an Identity-Per-Transaction (IPT) pipeline for a federal life sciences agency, generating a unique cryptographically scoped ephemeral credential for every file ingestion event and destroying it milliseconds later. We present the operational reality of running this in production: STS AssumeRole latency averaging 180ms, peak issuance rates during batch windows, the race condition we hit under high concurrency, and what happens when you need to debug a system whose credentials no longer exist.
We also address two hard problems directly. First, the secret-zero problem: the broker that issues ephemeral credentials is itself a root of trust. If it's compromised, the blast radius is bounded to 900 seconds rather than 90 days, but it is not zero. Second, the genomic privacy boundary: tokenizing 18 HIPAA identifiers does not anonymize a VCF file. This architecture eliminates credential-mediated access risk. It is not a genomic privacy framework. Those are different problems.
Attendees leave with a concrete reference pattern for eliminating Non-Human Identity risk in high-compliance storage systems, an honest accounting of where the architecture holds and where it defers, and open questions about trust bootstrapping that the field has not yet resolved.

Tristan McKinnon is Principal Investigator at Deterministic Systems Lab and a Senior Healthcare Data Engineer at Axle Informatics, where he designs zero-trust data pipelines processing genomic and clinical data at NIH scale under FedRAMP High constraints. He formalized the Identity-Per-Transaction (IPT) protocol, a framework applying ephemeral, transaction-scoped credentials to Non-Human Identity risk in high-compliance cloud environments, piloted at FedRAMP High scale on NIH data infrastructure. His research on AI integration in data science education is forthcoming in an Elsevier volume in Summer 2026.

author = {Tristan McKinnon},
title = {The Disposable Identity: Eliminating {Non-Human} Identity Risk in Federal Healthcare Pipelines},
year = {2026},
address = {Santa Clara, CA},
publisher = {USENIX Association},
month = jun
}